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Dear Dr. Roach: I hope you can answer some questions about myelodysplastic syndrome. What does it do to your body? Is there a known cause or cure? What is the prognosis? P.B.

Dear Dr. Roach: Is Januvia an effective drug for diabetes? What are the side-effects? M.A.A. Sitagliptin (Januvia) is an oral medication for diabetes mellitus.

How should hockey star Sidney Crosby, or my own child, be treated if he suffered a brain concussion? To answer this question, I interviewed Dr.

Dear Dr. Roach: I have lupus, so聽my kidneys and other organs are always of concern.

Dear Dr. Roach: My 14-year-old daughter has been diagnosed with and is being treated for depression. She has been suffering for at least two years now. I go over things in my mind and wonder if I had anything to do with her depression.

Dear Dr. Roach: My husband is 68. On a blood test in a doctor鈥檚 office, he had a CPK level of 694. He walks, on average, six miles per day, and drinks probably two or three glasses of wine four days a week, and a martini once or twice a week.

Dear Dr. Roach: What advice do you have for both doctors and patients for approaching medical marijuana use? What is your ideal vision of its future? C.C.

A friend recently asked: 鈥淕iff, what鈥檚 happened? You鈥檝e lost weight!鈥� He was wrong, as my weight has remained the same for years. But this is not the first time this has happened. It鈥檚 because I鈥檝e never liked dress shirts with tight collars.

Dear Dr. Roach: I am 76 years old and in excellent health, according to all my test results and doctors鈥� reports. I am very physically active, including playing tennis and golf, working out and fast walking.

Dear Dr. Roach: What is the best way to eliminate skin tags? Is there an over-the-counter item that will work effectively? There are many products that claim to remove them, but most don鈥檛. G.L.