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Dear Dr. Roach: I have had low GFR readings ranging from 53 to 37 for the past 15 years. I鈥檓 an 87-year-old woman in good health. I do strength training and Pilates, and am quite active walking my dog and doing my own yardwork.

Dear Dr. Roach: Could you please provide your recommendations on how we should conduct ourselves after we get the COVID vaccine? Please include an explanation of how immune we actually will be. T.S.

Dear Dr. Roach: I am currently on rituximab immunotherapy. I have had my first Moderna vaccine, and my second shot is in four weeks. My oncologist is not sure how the rituximab affects the effectiveness of the vaccine.

I鈥檇 like to know what kind of damage to look out for after being a heavy drinker between the ages of 19 and 40, at which age the drinking slowed to a comparative trickle.

Dear Dr. Roach: I鈥檝e had regular swab tests for COVID-19, which have always been negative. The last one was just a few days ago. I had an antibody test six weeks ago that also was negative, but my antibody test this time was strongly positive.

Dear Dr. Roach: What is celiac artery compression syndrome? I鈥檓 told I have this, and it鈥檚 causing an aneurysm that needs to get repaired. I found out on a scan taken for another reason. I have had some pain after eating. I.J.M.

Dear Dr. Roach: My doctor is insisting I take cholesterol medicine after I鈥檝e refused to take it for years. I am 66 years old, and my total cholesterol is 301 (triglycerides 76, HDL 83 and LDL 206). He has prescribed rosuvastatin, 20 mg a day.

Dear Dr. Roach: I have had more than 50 vaccinations in my life (I鈥檓 78), most of them while I was in the military. I have often wondered how the vaccine spreads throughout the body, as the shots are almost always given in the upper arm.

Dear Dr. Roach: My mother was diagnosed with right frontal lobe meningioma 17 years ago when she was 83 years old. Surgery was successful in that most of it was removed and it was found to be nonmalignant.

Dear Dr. Roach: My doctor recently retired. My new doctor is very concerned about my systolic blood pressure, which was 150. I made quarterly visits to my old doctor, who never had a comment about my pressure numbers.