DETROIT - The New York Yankees got through a game without another injury.
That was the only good news for the banged-up Bronx Bombers.
Miguel Cabrera drove in one of four runs in the fifth inning on a 4-for-4 day and the Detroit Tigers beat New York 8-4.
The Yankees got one of their five injured All-Stars back Saturday but lost for the fourth time in five games.
"There's still a lot of time to turn things around," right-hander Phil Hughes said.
Hughes (0-1) was one of the stars on the disabled list with Jeter, third baseman Alex Rodriguez, first baseman Mark Teixeira and outfielder Curtis Granderson.
He allowed four runs — three earned — on eight hits in four-plus innings on a day he was originally scheduled to make a rehabilitation start in the minors.
"I felt good early on," Hughes said. "The fifth inning was a big inning and I didn't make pitches when I needed to."
Max Scherzer (1-0) wasn't sharp, giving up four runs in five-plus innings, but he had plenty of run support.
New York chased Scherzer and had some success against Al Alburquerque before Darin Downs and Joaquin Benoit combined to pitch three scoreless innings to finish up for Detroit.
The Tigers will play for a series sweep Sunday in a matchup of aces, Detroit's Justin Verlander and New York's CC Sabathia.
"It's just a rough start," Yankees manager Joe Girardi said. "We've got to get it turned around."
Detroit led 5-1 after five innings. New York pulled within a run in the sixth, then let Detroit go ahead 7-4 in the home half.
Prince Fielder, one of six Tigers to drive in a run, had two RBIs a day after a two-homer, five-RBI performance against the Yankees.
Jayson Nix, filling in for Derek Jeter's injured backup, Eduardo Nunez, failed to field a routine grounder that allowed leadoff batter Austin Jackson to reach first. Jackson advanced to third on Cabrera's single and scored on Fielder's sacrifice fly.
Vernon Wells sent a 2-0 pitch into the left field seats in the second to make it 1-all. Torii Hunter kept it tied by throwing out Brennan Boesch — easily — on Francisco Cervelli's fly to right.
Jackson hit his first of three singles in the four-run fifth in which Hunter, Cabrera, Victor Martinez and Jhonny Peralta each had an RBI.
Hughes, who was to pitch a Triple-A game Saturday as he recovered from a back injury, had his outing ended when he gave up a double to Hunter in the pivotal inning. Boone Logan entered and gave up two hits and an unearned run, and getting only one out.
New York got back into the game, briefly, by scoring three in the sixth and chasing Scherzer with two walks and Travis Hafner's RBI single.
Alburquerque relieved Scherzer with a three-run lead, two on and no walks. He gave Wells a free pass on four pitches and had the good fortune of having a call overturned. Boesch lined out to Fielder and the first baseman stepped on the bag before Wells got there, but the first-base umpire signalled he was safe before conferring with the home-plate umpire to fix his mistake.
After Alburquerque gave up another walk, Lyle Overbay hit a two-run single to pull the Yankees within a run.
Detroit restored a comfortable cushion with Fielder's RBI groundout and Andy Dirks' single in the sixth along with strong pitching from Downs and Benoit.
New York reliever Joba Chamberlain let Detroit take a four-run lead into the ninth, loading the bases by giving up a single to Cabrera and walking Fielder and Martinez to set up Dirks for a sacrifice fly.
The bullpen is among Girardi's concerns.
"We definitely need to get it turned around," he said. "There's no doubt about that."
NOTES: Jeter, still recovering from left ankle surgery last October, did limited field work for the second consecutive day in Tampa, Fla. The shortstop fielded 41 grounders hit directly at him near the left-field fence, hit off a tee in a batting cage and played catch. ... Granderson could resume throwing next week as part of his rehabilitation program for a broken right forearm. The outfielder said Saturday he will have follow-up X-rays Tuesday and also hopes to be cleared to start swinging a fungo bat. ... Nunez, who was hit on the right biceps by a pitch Friday, said he's still sore with a lot of pain and swelling and probably won't play Sunday.