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Dear Dr. Roach: As I seem to be highly prone to urinary tract infections, I鈥檝e been using vaginal Estrace for decades. I鈥檓 82 years old. I鈥檝e developed serious gastroesophageal reflux disease, and note that there鈥檚 a connection with female hormones.

Dear Dr. Roach: I have always been a proponent of the attitude that 鈥渘o matter how much you make yourself look younger on the outside, you are still aging on the inside.

Dear Dr. Roach: I read with interest your recent column regarding the benefit of a colonoscopy for detecting colon cancer. I am 58 and started experiencing frequent light nausea about two months ago, a few days after getting my first Moderna vaccine.

Dear Dr. Roach: I鈥檓 a healthy woman. I recently had a whole-body thermography exam that highlighted my thyroid rather dramatically. Should I get a blood test for my thyroid and/or an ultrasound? E.D.

Dear Dr. Roach: My daughter is approximately five feet, four inches tall and weighs 230 pounds. She has been slowly putting on weight over the past several years.

Dear Dr. Roach: I am a 78-year-old polio survivor with severe osteoarthritis in my left shoulder, which is the side also affected by polio. I experience pain in varying degrees throughout the day, but at night the pain often wakes me up.

Dear Dr. Roach: I am responding to a recent letter from a reader anxious about undergoing a colonoscopy. One of her concerns was a possible perforation requiring additional surgery and a temporary colostomy.

Dear Dr. Roach: Please explain the difference between probiotics and prebiotics. I know they are both helpful for the digestive system, but I鈥檓 not sure why. A.B.

Dear Dr. Roach: My husband suffers from trigeminal neuralgia. This is often very painful for months at a time, then the pain will stop for a few months before it begins again. He does not want to begin taking an anti-seizure medication.

Dear Dr. Roach: I am an 86-year-old woman, and my sister is 91. We are both in good health, with normal health issues for people our age. My question is that we both have contracts with crematory companies, but we also intend to be organ donors.